The school is the most elite university in the Multiverse. It features five Colleges, which battle it out with their own takes on magic. Each college is named after an elder dragon who founded it. The Five Colleges are:
- Lorehold () - Passionate scholars and explorers who dedicate their studies to adventure and discovery. Their motto is "Leave no stone unturned."
- Prismari () - Mages who focus on the artistic side, using the elements to express themselves and their emotions. Their motto is "Express yourself with the elements."
- Quandrix () - They are mathematician wizards, seeing math and magic as one and the same. Their motto is "Math is magic."
- Silverquill () - They specialize in verbal magic, ranging from empowering poetry to biting arcane insults. Their motto is "Sharp style. Sharper wit."
- Witherbloom () - They are nature mages, on both sides of the spectrum, either empowering nature or exploiting it. Their motto is "Get your hands dirty."
- The Biblioplex
- The name Strixhaven is a combination of "Strix" and "haven". Strixes are magical birds from the mythology of classical antiquity, closely associated with witches. Strix is also a genus of owls.
- Mark Rosewater (September 1, 2020). "It may he a bit early to ask, but is Strixhaven the name of the whole plane or just the school?". Blogatog. Tumblr.
- Mark Rosewater (September 1, 2020). "Is it on a new plane or one we've visited in a set before?". Blogatog. Tumblr.
- Strixhaven Sneak Peek (Video). Weekly MTG. YouTube (February 19, 2021).
- The Zendikar Adventuring Party (Video). Magic: The Gathering. YouTube (September 1, 2020).